Evolution of the organisation of animal homeobox genes

Fluorescent chromosome in situ hybridisation of ANTP-class genes in Platynereis dumerilii.

The clustered organisation of many homeobox-containing genes can have functional implications, as with the Hox cluster, but can also reveal the evolutionary history of these important developmental control genes as well as the evolutionary dynamics of animal genomes. Patterns of gene origin, gene loss, linkage and clustering are being revealed by analysis of the genomes of representative taxa from across the animals.

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